The subsurface, surface, and ionospheric characteristics associated with the 29 July 2021 Mw 8.2 Chignik Earthquake are studied in detail using continuous Global Positioning System (cGPS) data over Alaska. The cGPS-inverted coseismic displacements demonstrate that the slip is distributed along the rupture area northeast of the epicenter with a maximum coseismic slip of ∼3.85 m occurring at a depth of ∼24.25 km. The vertical surface displacement estimated from the coseismic slip exhibits a similar deformation pattern with a maximum uplift of ∼1.0 m over the highly slip area. The ionospheric electron density perturbations associated with the Chignik earthquake were investigated using cGPS-derived Total Electron Content (TEC) data. Unlike the northeast-directed coseismic rupture and surface uplift, the ionospheric imprints of this event are more dominant southwest of the epicenter. This study reveals that the Earth's magnetic field and the ionospheric background electron density significantly controlled the TEC perturbation orientation and amplitudes rather than the rupture propagation and coseismic uplift pattern.